Zoë Blade's notebook

Southpaw

A southpaw keyboard layout has the number pad on the lefthand side instead of its usual location on the right.

Apparently the term comes from lefthanded people being called southpaws, most likely via baseball. Its use as a keyboard layout description seems to accidentally be ironic, as most people prefer to use the mouse with their dominant hand, as close to the letter keys as possible. This means that, amongst people who use a mouse more often than the number pad (which is almost everyone), it's mostly righthanded people who prefer southpaw keyboards and lefthanded people who specifically don't.

Having said that, it's a fairly obscure layout. Most people haven't heard of it, whether righthanded or lefthanded... and most keyboard layouts jettison the number pad anyway, from the C64 and Spectrum, through to laptops, various Apple desktops, and most mechanical keyboards.

Mechanical keyboards: Cherry MX switches | Gateron MX switches | Keychron switches | Southpaw | Switch (mechanical keyboard)